The emergence of Mycobacterium tuberculosis with complex drug resistance profiles necessitates a rapid and comprehensive drug susceptibility test for guidance of patient treatment. We developed two targeted-sequencing workflows based on Illumina MiSeq and Nanopore MinION for the prediction of drug resistance in M.

tuberculosis toward 12 antibiotics.A total of 163 M. tuberculosis isolates collected from Hong Kong and Ethiopia were subjected to a multiplex PCR for simultaneous amplification of 19 drug resistance-associated genetic regions.

The amplicons were then barcoded and sequenced in parallel on MiSeq and MinION in respective batch sizes of 24 and 12 samples. A web-based bioinformatics pipeline, BacterioChek-TB, was developed to translate the raw datasets into clinician-friendly reports.Both platforms successfully sequenced all samples with mean read depths of 1,127× and 1,649×, respectively.

The variant calling by MiSeq and MinION could achieve 100% agreement if variants with an allele frequency of <40% reported by MinION were excluded. Both workflows achieved a mean clinical sensitivity of 94.8% and clinical specificity of 98.0% when compared with phenotypic drug susceptibility test (pDST).

Turnaround times for the MiSeq and MinION workflows were 38 and 15 h, facilitating the delivery of treatment guidance at least 17-18 days earlier than pDST, respectively.

Recombinant Conus emaciatus Conotoxin Ec15a
MBS1018544-05mgEColi 0.5mg(E-Coli)
EUR 725

α-E-Catenin Antibody
E90730 100ul
EUR 255
Description: Available in various conjugation types.

α-E-Catenin (phospho-Ser652) rabbit pAb
E013439 100μg/100μl
EUR 255
Description: Available in various conjugation types.

α-E-Catenin (phospho-Ser652) rabbit pAb
E28PP1556 100μl
EUR 255
Description: Available in various conjugation types.

α-E-Catenin (phospho-Ser652) rabbit pAb
E44H14637 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

α-E-Catenin (phospho-Ser652) rabbit pAb
UB-GEN-16326 100 ul
EUR 200

Recombinant Echis carinatus Disintegrin EC3A
MBS1024789-002mgBaculovirus 0.02mg(Baculovirus)
EUR 990

Recombinant Echis carinatus Disintegrin EC3A
MBS1024789-002mgEColi 0.02mg(E-Coli)
EUR 555

Recombinant Echis carinatus Disintegrin EC3A
MBS1024789-002mgYeast 0.02mg(Yeast)
EUR 745

Recombinant Echis carinatus Disintegrin EC3A
MBS1024789-01mgEColi 0.1mg(E-Coli)
EUR 665

Recombinant Echis carinatus Disintegrin EC3A
MBS1024789-01mgYeast 0.1mg(Yeast)
EUR 870

EC55989_2174 Antibody
CSB-PA487466XA01ENM-02mg 0.2mg Ask for price
Description: Recombinant Escherichia coli (strain 55989 / EAEC) EC55989_2174 protein

EC55989_2174 Antibody
CSB-PA487466XA01ENM-10mg 10mg Ask for price
Description: Recombinant Escherichia coli (strain 55989 / EAEC) EC55989_2174 protein

EC55989_2495 Antibody
CSB-PA484952XA01ENM-02mg 0.2mg Ask for price
Description: Recombinant Escherichia coli (strain 55989 / EAEC) EC55989_2495 protein

EC55989_2495 Antibody
CSB-PA484952XA01ENM-10mg 10mg Ask for price
Description: Recombinant Escherichia coli (strain 55989 / EAEC) EC55989_2495 protein

EC55989_1114 Antibody
CSB-PA484131XA01ENM-02mg 0.2mg Ask for price
Description: Recombinant Escherichia coli (strain 55989 / EAEC) EC55989_1114 protein

EC55989_1114 Antibody
CSB-PA484131XA01ENM-10mg 10mg Ask for price
Description: Recombinant Escherichia coli (strain 55989 / EAEC) EC55989_1114 protein

Recombinant Echis carinatus sochureki Disintegrin EC6A
MBS1099744-002mgBaculovirus 0.02mg(Baculovirus)
EUR 990

Recombinant Echis carinatus sochureki Disintegrin EC6A
MBS1099744-002mgEColi 0.02mg(E-Coli)
EUR 555

Recombinant Echis carinatus sochureki Disintegrin EC6A
MBS1099744-002mgYeast 0.02mg(Yeast)
EUR 745

Recombinant Echis carinatus sochureki Disintegrin EC6A
MBS1099744-01mgEColi 0.1mg(E-Coli)
EUR 665

Recombinant Echis carinatus sochureki Disintegrin EC6A
MBS1099744-01mgYeast 0.1mg(Yeast)
EUR 870

Recombinant Saccharomyces cerevisiae UPF0507 protein EC1118_1M3_1541g (EC1118_1M3_1541g, EC1118_1M3_1552g), partial
MBS1113536-INQUIRE INQUIRE Ask for price

EC-5026
555766 5.0mg
EUR 90

EC-5062
MBS133100-INQUIRE INQUIRE Ask for price

EC0489
HY-114306 Get quote Ask for price
Description: EC0489, a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (FR). Refractory or metastatic Tumor[1]. Small molecule-agent conjugate (SMDC)[2].

EC5026
HY-135653 10 mg
EUR 535.72
Description: EC5026 (BPN-19186) is a first-in-class, non-opioid and orally active soluble Epoxide Hydrolase (sEH) inhibitor. EC5026 shows efficacy for inflammatory and neuropathic pain[1].

EC1454
HY-128937 Get quote Ask for price
Description: EC1454 is an anti-tumor compound, extracted from US20170348376A1[1].

EC1167
HY-128938 Get quote Ask for price
Description: EC1167 is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC)[1].

EC0488
HY-128939 Get quote Ask for price
Description: EC0488 is used to synthesize EC0531 with folate receptor (FR)-specific and anti-tumor activities[1].

EC0488
MBS3842883-10mg 10mg
EUR 1905

EC0488
MBS3842883-1mg 1mg
EUR 430

EC0488
MBS3842883-5mg 5mg
EUR 1165

EC0488
MBS3842883-5x10mg 5x10mg
EUR 8565

EC1167
MBS3842887-10mg 10mg
EUR 290

EC1167
MBS3842887-5mg 5mg
EUR 210

EC1167
MBS3842887-5x10mg 5x10mg
EUR 1305

EC1454
MBS3842891-10mg 10mg
EUR 1905

EC1454
MBS3842891-1mg 1mg
EUR 430

EC1454
MBS3842891-5mg 5mg
EUR 1165

EC1454
MBS3842891-5x10mg 5x10mg
EUR 8565

EC0489
MBS3843191-10mg 10mg
EUR 810

EC0489
MBS3843191-50mg 50mg
EUR 2370

EC0489
MBS3843191-5mg 5mg
EUR 465

EC0489
MBS3843191-5x50mg 5x50mg
EUR 10655

EC5026
MBS5753067-10mg 10mg
EUR 195

EC5026
MBS5753067-25mg 25mg
EUR 260

EC5026
MBS5753067-2mg 2mg
EUR 145

EC5026
MBS5753067-50mg 50mg
EUR 395

EC5026
MBS5753067-5mg 5mg
EUR 160

EC0488
MBS5766562-5mg 5mg
EUR 915

EC0488
MBS5766562-5x5mg 5x5mg
EUR 3970

EC1454
MBS5766563-5mg 5mg
EUR 915

EC1454
MBS5766563-5x5mg 5x5mg
EUR 3970

EC0489
MBS5768045-5mg 5mg
EUR 915

EC0489
MBS5768045-5x5mg 5x5mg
EUR 3970

EC2629
MBS5800171-5mg 5(mg
EUR 915

EC2629
MBS5800171-5x5mg 5x5(mg
EUR 3970

EC1167
T17930-10mg 10mg Ask for price
Description: EC1167

EC1167
T17930-1g 1g Ask for price
Description: EC1167

EC1167
T17930-1mg 1mg Ask for price
Description: EC1167

EC1167
T17930-50mg 50mg Ask for price
Description: EC1167

EC1167
T17930-5mg 5mg Ask for price
Description: EC1167

EC0488
T11144-10mg 10mg Ask for price
Description: EC0488

EC0488
T11144-1g 1g Ask for price
Description: EC0488

EC0488
T11144-1mg 1mg Ask for price
Description: EC0488

EC0488
T11144-50mg 50mg Ask for price
Description: EC0488

EC0488
T11144-5mg 5mg Ask for price
Description: EC0488

EC1454
T11145-10mg 10mg Ask for price
Description: EC1454

EC1454
T11145-1g 1g Ask for price
Description: EC1454

EC1454
T11145-1mg 1mg Ask for price
Description: EC1454

EC1454
T11145-50mg 50mg Ask for price
Description: EC1454

EC1454
T11145-5mg 5mg Ask for price
Description: EC1454

EC5026
T11147-10mg 10mg Ask for price
Description: EC5026

EC5026
T11147-1g 1g Ask for price
Description: EC5026

EC5026
T11147-1mg 1mg Ask for price
Description: EC5026

EC5026
T11147-50mg 50mg Ask for price
Description: EC5026

EC5026
T11147-5mg 5mg Ask for price
Description: EC5026

EC0489
T13672-10mg 10mg Ask for price
Description: EC0489

EC0489
T13672-1g 1g Ask for price
Description: EC0489

EC0489
T13672-1mg 1mg Ask for price
Description: EC0489

EC0489
T13672-50mg 50mg Ask for price
Description: EC0489

EC0489
T13672-5mg 5mg Ask for price
Description: EC0489

EC2629
T39757-10mg 10mg Ask for price
Description: EC2629

EC2629
T39757-1g 1g Ask for price
Description: EC2629

EC2629
T39757-1mg 1mg Ask for price
Description: EC2629

EC2629
T39757-50mg 50mg Ask for price
Description: EC2629

EC2629
T39757-5mg 5mg Ask for price
Description: EC2629

(Rac)-EC5026
HY-135653A 10 mg
EUR 1569.29
Description: (Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, page 39, has a Ki of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia with Lewy Bodies (DLB)[1].

(Rac)-EC5026
T9832-10mg 10mg Ask for price
Description: (Rac)-EC5026

(Rac)-EC5026
T9832-1g 1g Ask for price
Description: (Rac)-EC5026

(Rac)-EC5026
T9832-1mg 1mg Ask for price
Description: (Rac)-EC5026

(Rac)-EC5026
T9832-50mg 50mg Ask for price
Description: (Rac)-EC5026

(Rac)-EC5026
T9832-5mg 5mg Ask for price
Description: (Rac)-EC5026

Recombinant Escherichia coli CinA-like protein (EC55989_2495)
MBS1190398-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1270

Recombinant Escherichia coli CinA-like protein (EC55989_2495)
MBS1190398-002mgEColi 0.02mg(E-Coli)
EUR 945

Recombinant Escherichia coli CinA-like protein (EC55989_2495)
MBS1190398-002mgYeast 0.02mg(Yeast)
EUR 1065

Recombinant Escherichia coli CinA-like protein (EC55989_2495)
MBS1190398-01mgEColi 0.1mg(E-Coli)
EUR 1135

Recombinant Escherichia coli CinA-like protein (EC55989_2495)
MBS1190398-01mgYeast 0.1mg(Yeast)
EUR 1210

EC1118_1N9_3125g Antibody
CSB-PA510583XA01SVN-02mg 0.2mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1N9_3125g protein

EC1118_1N9_3125g Antibody
CSB-PA510583XA01SVN-10mg 10mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1N9_3125g protein

EC1118_1M3_1541g Antibody
CSB-PA513183XA01SVN-02mg 0.2mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1M3_1541g protein

EC1118_1M3_1541g Antibody
CSB-PA513183XA01SVN-10mg 10mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1M3_1541g protein

EC1118_1M3_2531g Antibody
CSB-PA513184XA01SVN-02mg 0.2mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1M3_2531g protein

EC1118_1M3_2531g Antibody
CSB-PA513184XA01SVN-10mg 10mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1M3_2531g protein

EC1118_1M3_2520g Antibody
CSB-PA513912XA01SVN-02mg 0.2mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1M3_2520g protein

EC1118_1M3_2520g Antibody
CSB-PA513912XA01SVN-10mg 10mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1M3_2520g protein

EC1118_1L10_0100g Antibody
CSB-PA513181XA01SVN-02mg 0.2mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1L10_0100g protein

EC1118_1L10_0100g Antibody
CSB-PA513181XA01SVN-10mg 10mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1L10_0100g protein

EC1118_1B15_2135g Antibody
CSB-PA514204XA01SVN-02mg 0.2mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1B15_2135g protein

EC1118_1B15_2135g Antibody
CSB-PA514204XA01SVN-10mg 10mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) EC1118_1B15_2135g protein

Rabbit anti-Escherichia coli (strain 55989/EAEC) EC55989_1114 Polyclonal Antibody
MBS7174499-INQUIRE INQUIRE Ask for price

Rabbit anti-Escherichia coli (strain 55989/EAEC) EC55989_2495 Polyclonal Antibody
MBS7175251-INQUIRE INQUIRE Ask for price

Rabbit anti-Escherichia coli (strain 55989/EAEC) EC55989_2174 Polyclonal Antibody
MBS7177554-INQUIRE INQUIRE Ask for price

Recombinant Saccharomyces cerevisiae Vacuolar membrane protein EC1118_1N9_3125g (EC1118_1N9_3125g)
MBS1154053-INQUIRE INQUIRE Ask for price

Recombinant Saccharomyces cerevisiae Uncharacterized protein EC1118_1M3_2531g (EC1118_1M3_2531g)
MBS1199352-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1300

Recombinant Saccharomyces cerevisiae Uncharacterized protein EC1118_1M3_2531g (EC1118_1M3_2531g)
MBS1199352-002mgEColi 0.02mg(E-Coli)
EUR 985

Recombinant Saccharomyces cerevisiae Uncharacterized protein EC1118_1M3_2531g (EC1118_1M3_2531g)
MBS1199352-002mgYeast 0.02mg(Yeast)
EUR 1095

Recombinant Saccharomyces cerevisiae Uncharacterized protein EC1118_1M3_2531g (EC1118_1M3_2531g)
MBS1199352-01mgEColi 0.1mg(E-Coli)
EUR 1150

Recombinant Saccharomyces cerevisiae Uncharacterized protein EC1118_1M3_2531g (EC1118_1M3_2531g)
MBS1199352-01mgYeast 0.1mg(Yeast)
EUR 1245

Recombinant Saccharomyces cerevisiae Vacuolar membrane protein EC1118_1N9_3125g (EC1118_1N9_3125g)
MBS7040023-002mg 0.02mg
EUR 1625

Recombinant Saccharomyces cerevisiae Vacuolar membrane protein EC1118_1N9_3125g (EC1118_1N9_3125g)
MBS7040023-01mg 0.1mg
EUR 2580

Recombinant Saccharomyces cerevisiae Vacuolar membrane protein EC1118_1N9_3125g (EC1118_1N9_3125g)
MBS7040023-5x01mg 5x0.1mg
EUR 11575

EC330
462567 1.0mg
EUR 260

EC-109
ABC-TC508S 1 vial Ask for price
Description: Tissue: Esophagus; Esophageal cancer cell lines.

EC330
MBS132904-INQUIRE INQUIRE Ask for price

EC144
HY-13479 10 mg
EUR 963.22
Description: EC144 is a potent and selective inhibitor of heat shock protein 90 (Hsp90) with an IC50 of 1.1 nM. EC144 inhibits tumor growth and causes partial tumor regressions. EC144 has the potential for the research of cancer diseases[1]. EC144 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

EC330
HY-100949 50mg
EUR 1428.59
Description: EC330 is a leukemia inhibitory factor (LIF) inhibitor. EC330 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

EC089
HY-128940 Get quote Ask for price
Description: EC089 is a cleavable linker used in conjugates of tubulysins and folates, and extracted from patent WO2011069116A1[1].

EC359
HY-120142 10 mg
EUR 1785.74
Description: EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a Kd of 10.2 nM, which directly interacts with LIFR to effectively block LIF/LIFR interactions[1]. EC359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

EC330
MBS3610713-10mg 10mg
EUR 555

EC330
MBS3610713-25mg 25mg
EUR 880

EC330
MBS3610713-5mg 5mg
EUR 415

EC330
MBS3610713-5x25mg 5x25mg
EUR 3630

EC330
MBS3840056-10mg 10mg
EUR 800

EC330
MBS3840056-1mg 1mg
EUR 220

EC330
MBS3840056-50mg 50mg
EUR 2290

EC330
MBS3840056-5mg 5mg
EUR 495

EC330
MBS3840056-5x50mg 5x50mg
EUR 10300

EC089
MBS3842879-10mg 10mg
EUR 1905

EC089
MBS3842879-1mg 1mg
EUR 430

EC089
MBS3842879-5mg 5mg
EUR 1165

EC089
MBS3842879-5x10mg 5x10mg
EUR 8565

EC359
MBS5753066-100mg 100mg
EUR 2840

EC359
MBS5753066-50mg 50mg
EUR 1905

EC359
MBS5753066-5x100mg 5x100mg
EUR 12620

EC330
MBS5752441-10mg 10mg
EUR 380

EC330
MBS5752441-1mg 1mg
EUR 170

EC330
MBS5752441-25mg 25mg
EUR 640

EC330
MBS5752441-50mg 50mg
EUR 920

EC330
MBS5752441-5mg 5mg
EUR 290

EC089
T17929-10mg 10mg Ask for price
Description: EC089

EC089
T17929-1g 1g Ask for price
Description: EC089

EC089
T17929-1mg 1mg Ask for price
Description: EC089

EC089
T17929-50mg 50mg Ask for price
Description: EC089

EC089
T17929-5mg 5mg Ask for price
Description: EC089

EC359
T11146-10mg 10mg Ask for price
Description: EC359

EC359
T11146-1g 1g Ask for price
Description: EC359

EC359
T11146-1mg 1mg Ask for price
Description: EC359

EC359
T11146-50mg 50mg Ask for price
Description: EC359

EC359
T11146-5mg 5mg Ask for price
Description: EC359

EC330
T7293-10mg 10mg Ask for price
Description: EC330

EC330
T7293-1g 1g Ask for price
Description: EC330

EC330
T7293-1mg 1mg Ask for price
Description: EC330

EC330
T7293-50mg 50mg Ask for price
Description: EC330

EC330
T7293-5mg 5mg Ask for price
Description: EC330

EC1167 (hydrochloride)
HY-128938A 10 mg
EUR 1569.29
Description: EC1167 hydrochloride is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 hydrochloride has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC)[1].

Recombinant Saccharomyces cerevisiae Vacuolar membrane protein EC1118_1N9_3125g (EC1118_1N9_3125g), partial
MBS7069187-INQUIRE INQUIRE Ask for price

Recombinant Saccharomyces cerevisiae Putative uncharacterized protein EC1118_1L10_0100g (EC1118_1L10_0100g)
MBS1071433-INQUIRE INQUIRE Ask for price

Recombinant Saccharomyces cerevisiae Putative uncharacterized protein EC1118_1L10_0100g (EC1118_1L10_0100g)
MBS7039728-002mg 0.02mg
EUR 1425

Recombinant Saccharomyces cerevisiae Putative uncharacterized protein EC1118_1L10_0100g (EC1118_1L10_0100g)
MBS7039728-01mg 0.1mg
EUR 2390

Recombinant Saccharomyces cerevisiae Putative uncharacterized protein EC1118_1L10_0100g (EC1118_1L10_0100g)
MBS7039728-5x01mg 5x0.1mg
EUR 10715

EC-109 cells
C0013001 One Frozen vial
EUR 620

EC-109 Cells
116149 1 Vial Ask for price

EC-109 Cells
116149L 0.5 mg Ask for price

EC-109 Cells
116149R 100 µg Ask for price

External printer for EC-35 and EC-45
1001502 each
EUR 278

Recombinant Saccharomyces cerevisiae Probable zinc metalloprotease EC1118_1B15_2135g (EC1118_1B15_2135g), partial
MBS1005436-1mgEColi 1mg(E-Coli)
EUR 3435

Recombinant Saccharomyces cerevisiae Probable zinc metalloprotease EC1118_1B15_2135g (EC1118_1B15_2135g), partial
MBS1005436-1mgYeast 1mg(Yeast)
EUR 3925

Recombinant Saccharomyces cerevisiae Putative uncharacterized protein EC1118_1L10_0100g (EC1118_1L10_0100g), partial
MBS7069358-INQUIRE INQUIRE Ask for price

The higher cost per sample on the MinION platform ($71.56) versus the MiSeq platform ($67.83) was attributed to differences in batching capabilities.Our study demonstrates the interchangeability of MiSeq and MinION platforms for generation of accurate and actionable results for the treatment of tuberculosis.