These days, many of the preimplantation genetic testing (PGT) is carried out with a method of complete chromosome screening and trophectoderm biopsy. However, sufferers with ovarian insufficiency could not have competent blastocysts. Within the current examine, we aimed to ascertain the worth of a number of annealing and looping-based amplification cycle (MALBAC)-based next-generation sequencing (NGS) for PGT in day-Three embryos. A complete of 94.3% (1168/1239) of embryos yielded informative outcomes, and the general embryo euploid charge was 21.9% (256/1168).

Total, 225 embryos have been transferred in 169 cycles with a medical being pregnant charge of 49.1% (83/169). The stay start and implantation charges have been 47.3% (80/169) and 44.4% (100/225), respectively. Double embryos switch confirmed greater medical being pregnant and stay start charges in contrast with single embryo switch, however the implantation charges have been comparable (44.2% vs. 44.6%, P > 0.05). The euploid charge for reciprocal translocations (16.1%) was considerably decrease than that for Robertsonian translocations (28.0%, P < 0.01) and inversions (28.0%, P < 0.01). Nonetheless, greater percentages of embryos with de novo abnormalities have been noticed with Robertsonian translocations (23.3%, P < 0.01) and inversions (30.5%, P < 0.01) than with reciprocal translocations (11.6%).

From Sep. 2016 to Aug. 2018, a complete of six {couples} participated on this examine. 4 instances carried DMD exon deletions and two carried exon duplications. Trophectoderm cells have been biopsied at day 5 or 6 and NGS was used within the genetic testing of the biopsied cells after whole-genome amplification. We developed a brand new method-DIRected Embryonic Cell Testing of Exon Deletion/Duplication (DIRECTED) to instantly detect the single-gene mutation by NGS. Linage evaluation based mostly on single-nucleotide polymorphism (SNP) was used to validate the outcomes from DIRECTED.

 Within the 4 deletion instances, DIRECTED was used to detect DMD exon deletion in 16 biopsied embryos. All DIRECTED outcomes have been in line with linkage evaluation, indicating this technique was dependable in detecting deletions round 1 Mb. Within the two instances carrying exon duplications, no blastocyst was obtained for biopsy. Nonetheless, preliminary experiment outcomes urged that DIRECTED may be used for direct detection of exon duplications in embryos. We demonstrated that NGS for PGT on day-Three embryos is an efficient medical software, significantly for sufferers with a diminished ovarian reserve and restricted embryos.

Subsequent-Era Sequencing (NGS)-Primarily based Preimplantation Genetic Testing for Aneuploidy (PGT-A) of Trophectoderm Biopsy for Recurrent Implantation Failure (RIF) Sufferers: a Retrospective Research

Recurrent implantation failure (RIF) is an intrigue situation throughout in vitro fertilization (IVF) cycles or intracytoplasmic sperm injection (ICSI) remedies. The aim of this retrospective examine is to discover the worth of next-generation sequencing (NGS)-based preimplantation genetic testing for aneuploidy (PGT-A) of trophectoderm biopsy within the medical outcomes for RIF sufferers with superior age. A complete of 265 RIF sufferers, who underwent 346 oocyte retrieval cycles and 250 PGT-A cycles, have been categorised as two teams in keeping with the feminine age, together with < 38 and ≥ 38 years outdated teams.

The 2 teams have been statistically comparable in baseline traits. The part of aneuploid embryos was considerably greater in superior age group than in youthful age group (68.9 vs 39.9%, P < 0.001). However there have been no statistically vital variations in being pregnant charge (43.5 vs 64.7%), medical being pregnant charge (39.1 vs 48.0%), implantation charge (39.1 vs 51.0%), and miscarriage charge (4.Three vs 7.8%) per embryo switch (ET) between the 2 teams. Outcomes counsel that the embryo-related issue performs an important position in RIF. Maternal age doesn’t affect the implantation potential of euploid blastocysts.

The NGS-based PGT-A involving trophectoderm biopsy is efficacious for RIF sufferers of superior age by enhancing their medical outcomes. In conclusion, the NGS-based PGT-A involving trophectoderm biopsy could symbolize a invaluable complement to the present RIF administration. Nonetheless, these findings ought to be additional validated in a well-designed randomized managed trial.

A Rapid NGS-Based Preimplantation Genetic Testing for Chromosomal Abnormalities in Day-3 Blastomere Biopsy Allows Embryo Transfer Within the Same Treatment Cycle

Sanger sequencing is not all the time needed based mostly on a single-center validation of 1109 NGS variants in 825 medical exomes

Regardless of the improved accuracy of next-generation sequencing (NGS), it’s extensively accepted that variants have to be validated utilizing Sanger sequencing earlier than reporting. Validation of all NGS variants significantly will increase the turnaround time and prices of medical prognosis. We comprehensively assessed this want in 1109 variants from 825 medical exomes, the biggest pattern set up to now assessed utilizing Illumina chemistry reported. With a concordance of 100%, we conclude that Sanger sequencing might be very helpful as an inside high quality management, however not a lot as a verification technique for high-quality single-nucleotide and small insertion/deletions variants.

Laboratories would possibly validate and set up their very own thresholds earlier than discontinuing Sanger affirmation research. We additionally increase and validate 23 copy quantity variations detected by exome sequencing in 20 samples, observing a concordance of 95.65%.  47 sufferers have been enrolled for additional evaluation. A last prognosis was accessible in 27 instances together with Eight adverse controls. In 43/47 (91.5%) of sufferers a KRAS- and/or GNAS-mutation was identified by NGS. 27.0% of the KRAS-mutated and 10.0% of the GNAS-mutated lesions harbored a number of mutations. KRAS/GNAS-testing by NGS, cytology, and CEA had a sensitivity and specificity of 94.7/100%, 38.1/100% and 42.1/75.0%, respectively.

Accuris™ UV Transilluminator
BM0298 Ea
EUR 1306

PMA-Lite LED Photolysis Device
E90002 1EA
EUR 2211
Description: Minimum order quantity: 1 unit of 1EA

Gel-Bright LED Gel Illuminator
E90003 1EA
EUR 773
Description: Minimum order quantity: 1 unit of 1EA

Glo-Plate Blue LED Illuminator
E90004 1EA
EUR 717
Description: Minimum order quantity: 1 unit of 1EA

uv table blue led 20x20 cm
VLECX-20BLUE ea
EUR 1535

Accuris™ UV Transilluminator, 230V input
BM0299 Ea
EUR 1306

WUV-M20, UV Transilluminator, 312nm, 100V
3532197 1unit
EUR 1627

WUV-M20, UV Transilluminator, 312nm, 220V
3532198 1unit
EUR 1627

Sealing Mats for 96 Well Format
GP501 5 mats
EUR 147

uv transilluminator 20x20cm, 312nm, 50/100% switch
UVTR2200 ea
EUR 1161

PGE2 Multi-Format EIA kit (One Plate)
K051-H1 1x96 well plate
EUR 379

PGE2 Multi-Format EIA kit (Five Plate)
K051-H5 5x96 well plate
EUR 1344

Pressure Sealing Mats for 384 Well Format
GP504 5 mats
EUR 196

LARGE siRNA
20-abx922269
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

LARGE siRNA
20-abx922270
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

LARGE Peptide
42-560P 0.1 mg
EUR 338
Description: (IN) LARGE Peptide

LARGE Peptide
42-561P 0.1 mg
EUR 338
Description: (NT) LARGE Peptide

LARGE antibody
70R-6856 50 ug
EUR 467
Description: Rabbit polyclonal LARGE antibody raised against the middle region of LARGE

CytoSelect 96-Well Phagocytosis Assay (E. coli, Colorimetric Format)
CBA-222 96 assays
EUR 693
Description: Phagocytosis can be assayed by measuring the engulfment of a cell "substrate". However, traditional assays require tedious cell counting under a microscope. Our CytoSelect 96-Well Phagocytosis Assay, E. coli Substrate provides a more accurate, user-friendly, high-throughput alternative to the standard phagocytosis assay. The assay may be adapted for use with 24-well or 48-well plates.

LARGE ELISA Kit| chicken Glycosyltransferase-like protein LARGE
EF012373 96 Tests
EUR 689

LARGE cloning plasmid
CSB-CL012749HU-10ug 10ug
EUR 745
Description: A cloning plasmid for the LARGE gene.

Spatulas (Large Pack)
SPAT1 50pack
EUR 301
Description: Individually wrapped spatulas. RNase/DNase free, non-pyrogenic, antistatic, sterile, plastic. Pack of 50.

Anti-LARGE antibody
STJ11100708 50 µl
EUR 287
Description: This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Large-CRP OmcBProtein
20-abx600013
  • EUR 843.00
  • EUR 439.00
  • EUR 1274.00
  • EUR 1636.00
  • EUR 551.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 500 ug
  • 50 ug

Large-CRP OmcBProtein
20-abx600014
  • EUR 2764.00
  • EUR 1734.00
  • 100 ug
  • 50 ug

LARGE Rabbit pAb
A19515-100ul 100 ul Ask for price

LARGE Rabbit pAb
A19515-200ul 200 ul Ask for price

LARGE Rabbit pAb
A19515-20ul 20 ul Ask for price

LARGE Rabbit pAb
A19515-50ul 50 ul
EUR 308

anti- LARGE antibody
FNab04697 100µg
EUR 548.75
Description: Antibody raised against LARGE

LARGE Blocking Peptide
33R-1247 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CRYM antibody, catalog no. 70R-1992

Anti-LARGE antibody
PAab04697 100 ug
EUR 386

Retinol Binding Protein (RBP) Multi-format EIA Kit (One Plate)
K062-H1 1x96 well plate
EUR 369

Retinol Binding Protein (RBP) Multi-format EIA Kit (Five Plate)
K062-H5 5x96 well plate
EUR 1344

Recombinant Like Glycosyltransferase (LARGE)
4-RPH936Hu01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Like Glycosyltransferase expressed in: E.coli

Mouse LARGE shRNA Plasmid
20-abx971279
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Measuring Spoon (Large Pack)
SPN1 200pack
EUR 479
Description: Individually wrapped 1.2mL spoons. Sterile. Pack of 200.

Caspase-12 Antibody (Large)
24208-100ul 100ul
EUR 390

Like Glycosyltransferase (LARGE) Antibody
20-abx128114
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Like Glycosyltransferase (LARGE) Antibody
20-abx124463
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Large-CRP OmcB Protein
20-abx600002
  • EUR 1970.00
  • EUR 3919.00
  • EUR 2541.00
  • EUR 1414.00
  • 100 ug
  • 1 mg
  • 500 ug
  • 50 ug

Large-CRP OmcB Protein
20-abx600012
  • EUR 2486.00
  • EUR 1455.00
  • EUR 1622.00
  • EUR 1107.00
  • 1 mg
  • 200 ug
  • 500 ug
  • 50 ug

Human LARGE shRNA Plasmid
20-abx956100
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Rubisco Large Chain Antibody
20-abx134717
  • EUR 356.00
  • EUR 537.00
  • EUR 217.00
  • 100 ul
  • 200 ul
  • 30 ul

Like Glycosyltransferase (LARGE) Antibody
abx432911-200ul 200 ul
EUR 384

Like Glycosyltransferase (LARGE) Antibody
abx432912-200ul 200 ul
EUR 286

Rubisco (Large Chain) Antibody
20-abx159680
  • EUR 272.00
  • EUR 230.00
  • 100 ug
  • 50 ug

Rubisco (Large Chain) Antibody
20-abx159681
  • EUR 272.00
  • EUR 230.00
  • 100 ug
  • 50 ug

Like Glycosyltransferase (LARGE) Antibody
abx234697-100ug 100 ug
EUR 509

Rubisco Antibody (Large Chain)
abx332842-100ul 100 ul
EUR 425

LARGE ELISA KIT|Human
EF010620 96 Tests
EUR 689

Chicken LARGE ELISA KIT
ELI-08774c 96 Tests
EUR 928

Caspase-12 Antibody (Large)
3195-002mg 0.02 mg
EUR 171.82
Description: Caspase-12 Antibody: (Large)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.

Caspase-12 Antibody (Large)
3195-01mg 0.1 mg
EUR 436.42
Description: Caspase-12 Antibody: (Large)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.

Caspase-12 Peptide (Large)
3195P 0.05 mg
EUR 164.75
Description: Caspase-12 peptide (Large)

pSG5 Large T Plasmid
PVT15908 2 ug
EUR 325

LARGE Recombinant Protein (Rat)
RP207821 100 ug Ask for price

LARGE Recombinant Protein (Human)
RP040651 100 ug Ask for price

LARGE Recombinant Protein (Mouse)
RP146864 100 ug Ask for price

CytoSelect 24-Well Cell Migration Assay (8 µm, Colorimetric Format), Trial Size
CBA-100-T 4 assays
EUR 299
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 8 µm pore size is suitable for most cell types including epithelial cells, fibroblasts, and cancer cell lines.

CytoSelect 24-Well Cell Migration Assay (8 µm, Fluorometric Format), Trial Size
CBA-101-T 4 assays
EUR 299
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 8 µm pore size is suitable for most cell types including epithelial cells, fibroblasts, and cancer cell lines.

CytoSelect 24-Well Cell Migration Assay (5 µm, Fluorometric Format), Trial Size
CBA-102-T 4 assays
EUR 299
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 5 µm pore size is ideal for monocytes / macrophages.

CytoSelect 24-Well Cell Migration Assay (3 µm, Fluorometric Format), Trial Size
CBA-103-T 4 assays
EUR 299
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 3 µm pore size is best for the smallest cells including neutrophils and other leukocytes.

CytoSelect 24-Well Cell Invasion Assay (Basement Membrane, Colorimetric Format), Trial Size
CBA-110-T 4 assays
EUR 322
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with ECM matrix gel (basement membrane), a protein mix isolated from EHS tumor cells.

CytoSelect 24-Well Cell Invasion Assay (Basement Membrane, Fluorometric Format), Trial Size
CBA-111-T 4 assays
EUR 322
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with ECM matrix gel (basement membrane), a protein mix isolated from EHS tumor cells.

Scoops Material Stainless Steel, Large
SP076 1 UNIT
EUR 57.4

h LARGE inducible lentiviral particles
LVP603 1x107 IFU/ml x 200ul
EUR 451
Description: Pre-made over-expression lentivirus for expressing human target: LARGE (like-glycosyltransferase (LARGE)), [alternative names: MDC1D; MDDGA6; MDDGB6]. The sub-cloned codon sequence is identical (100% match) to CDS region in NCBI ID: NM_133642.3. It also contains a RFP-Blasticidin dual selection marker.

Rubisco(Large Chain) Monoclonal Antibody
EM1214-100ul 100ul
EUR 279
Description: A Mouse Monoclonal antibody against Rubisco(Large Chain) from Plants. This antibody is tested and validated for WB, ELISA

Rubisco(Large Chain) Monoclonal Antibody
EM1214-50ul 50ul
EUR 207
Description: A Mouse Monoclonal antibody against Rubisco(Large Chain) from Plants. This antibody is tested and validated for WB, ELISA

SV40 large T antigen NLS
HY-P0310 5mg
EUR 491

Large DNA Fragment Extraction Kit
FYG204-100P 100 Preps Ask for price

Large DNA Fragment Extraction Kit
FYG204-300P 300 Preps Ask for price

Polyclonal Caspase-12 Antibody (Large)
APR06327G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 (Large). This antibody is tested and proven to work in the following applications:

Ribosomal Protein, Large, P0 Antibody
20-abx115279
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Rubisco (Large Chain) Monoclonal Antibody
ABM40217-003ml 0.03ml
EUR 158
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen Protein

Rubisco (Large Chain) Monoclonal Antibody
ABM40217-01ml 0.1ml
EUR 289
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen Protein

Rubisco (Large Chain) Monoclonal Antibody
ABM40217-02ml 0.2ml
EUR 414
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen Protein

Rubisco (Large Chain) Monoclonal Antibody
ABM40218-003ml 0.03ml
EUR 158
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen Protein

Rubisco (Large Chain) Monoclonal Antibody
ABM40218-01ml 0.1ml
EUR 289
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen Protein

Rubisco (Large Chain) Monoclonal Antibody
ABM40218-02ml 0.2ml
EUR 414
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen Protein

Large T Antigen (LT) Protein
20-abx654150
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Like Glycosyltransferase (LARGE) Protein
20-abx166585
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Large T Antigen (LT) Antibody
20-abx177313
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug

Recombinant MeV Large Polymerase Protein
VAng-Lsx0385-inquire inquire Ask for price
Description: Recombinant MeV Large Polymerase containing the large polymerase immunodominant regions, 58-149 amino acids was expressed in E. coli and purified by proprietary chromatographic technique.

Anti-Rubisco (Large Chain) antibody
STJ97527 200 µl
EUR 197
Description: Mouse monoclonal to Rubisco (Large Chain) (3G7).

Anti-Rubisco (Large Chain) antibody
STJ97528 200 µl
EUR 197
Description: Mouse monoclonal to Rubisco (Large Chain) (1H1).

Anti-LARGE (aa421-433) antibody
STJ72207 100 µg
EUR 359

Anti-LARGE (N-terminus) antibody
STJ72208 100 µg
EUR 260

Large ORF Vector (Rat) (pORF)
ORF069275 1.0 ug DNA
EUR 506

LARGE ORF Vector (Human) (pORF)
ORF013551 1.0 ug DNA
EUR 354

Large ORF Vector (Mouse) (pORF)
ORF048956 1.0 ug DNA
EUR 506

Bst DNA Polymerase, Large Fragment
M1213-200
EUR 289

Bsu DNA Polymerase Large Fragment
M1214-200
EUR 398

Bst DNA Polymerase Large Fragment
P701-01 800 U
EUR 122

Bst DNA Polymerase Large Fragment
P701-02 8000 U
EUR 271

96-Well Cellular Senescence Assay Kit (SA-?-gal Activity, Fluorometric Format), Trial Size
CBA-231-T 24 assays
EUR 345
Description: Our Cellular Senescence Activity Assay provides an efficient method to measure Senescence Associated (SA) ß-galactosidase activity. SA-ß-Gal catalyzes the hydrolysis of X-gal, which produces a blue color in senescent cells. Quantify senescence using a fluorescence plate reader.

Recombinant Large Multifunctional Peptidase 7 (LMP7)
4-RPB556Hu01
  • EUR 504.99
  • EUR 238.00
  • EUR 1618.72
  • EUR 606.24
  • EUR 1112.48
  • EUR 401.00
  • EUR 3896.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Large Multifunctional Peptidase 7 expressed in: E.coli

Recombinant Large Multifunctional Peptidase 7 (LMP7)
4-RPB556Mu01
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Large Multifunctional Peptidase 7 expressed in: E.coli

Recombinant Large Multifunctional Peptidase 7 (LMP7)
4-RPB556Ra01
  • EUR 565.92
  • EUR 254.00
  • EUR 1847.20
  • EUR 682.40
  • EUR 1264.80
  • EUR 442.00
  • EUR 4468.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Large Multifunctional Peptidase 7 expressed in: E.coli

Recombinant Large Multifunctional Peptidase 2 (LMP2)
4-RPA329Hu01
  • EUR 383.14
  • EUR 205.00
  • EUR 1161.76
  • EUR 453.92
  • EUR 807.84
  • EUR 319.00
  • EUR 2754.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Large Multifunctional Peptidase 2 expressed in: E.coli

Recombinant Large Multifunctional Peptidase 2 (LMP2)
4-RPA329Mu01
  • EUR 499.62
  • EUR 236.00
  • EUR 1598.56
  • EUR 599.52
  • EUR 1099.04
  • EUR 397.00
  • EUR 3846.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Large Multifunctional Peptidase 2 expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Hu01
  • EUR 535.46
  • EUR 246.00
  • EUR 1732.96
  • EUR 644.32
  • EUR 1188.64
  • EUR 421.00
  • EUR 4182.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Calpain 1, Large Subunit expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Hu02
  • EUR 535.46
  • EUR 246.00
  • EUR 1732.96
  • EUR 644.32
  • EUR 1188.64
  • EUR 421.00
  • EUR 4182.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Calpain 1, Large Subunit expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Mu01
  • EUR 548.00
  • EUR 250.00
  • EUR 1780.00
  • EUR 660.00
  • EUR 1220.00
  • EUR 430.00
  • EUR 4300.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Calpain 1, Large Subunit expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Mu02
  • EUR 548.00
  • EUR 250.00
  • EUR 1780.00
  • EUR 660.00
  • EUR 1220.00
  • EUR 430.00
  • EUR 4300.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Calpain 1, Large Subunit expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Ra01
  • EUR 556.96
  • EUR 252.00
  • EUR 1813.60
  • EUR 671.20
  • EUR 1242.40
  • EUR 436.00
  • EUR 4384.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Calpain 1, Large Subunit expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Ra02
  • EUR 556.96
  • EUR 252.00
  • EUR 1813.60
  • EUR 671.20
  • EUR 1242.40
  • EUR 436.00
  • EUR 4384.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Calpain 1, Large Subunit expressed in: E.coli

Recombinant Discs, Large Homolog 3 (DLG3)
4-RPG764Hu01
  • EUR 490.66
  • EUR 234.00
  • EUR 1564.96
  • EUR 588.32
  • EUR 1076.64
  • EUR 391.00
  • EUR 3762.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Discs, Large Homolog 3 expressed in: E.coli

Recombinant Discs, Large Homolog 5 (DLG5)
4-RPD069Hu01
  • EUR 422.56
  • EUR 216.00
  • EUR 1309.60
  • EUR 503.20
  • EUR 906.40
  • EUR 346.00
  • EUR 3124.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Discs, Large Homolog 5 expressed in: E.coli

Recombinant Discs, Large Homolog 5 (DLG5)
4-RPD069Mu01
  • EUR 449.44
  • EUR 223.00
  • EUR 1410.40
  • EUR 536.80
  • EUR 973.60
  • EUR 364.00
  • EUR 3376.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Discs, Large Homolog 5 expressed in: E.coli

Like Glycosyltransferase (LARGE) Polyclonal Antibody (Human)
4-PAH936Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Like Glycosyltransferase (LARGE)

Recombinant Calpain 2, Large Subunit (CAPN2)
4-RPC358Hu01
  • EUR 476.32
  • EUR 230.00
  • EUR 1511.20
  • EUR 570.40
  • EUR 1040.80
  • EUR 382.00
  • EUR 3628.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Calpain 2, Large Subunit expressed in: E.coli

FD Rapid GolgiStain™ Kit (large)
PK401 kit
EUR 816

Rat Disks large homolog 3 (Dlg3)
1-CSB-EP717292RA
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Rat Disks large homolog 3(Dlg3) expressed in E.coli

Rubisco Mouse Polyclonal Antibody(Large Chain)
CSB-PA060093-
EUR 335
Description: A polyclonal antibody against Rubisco Mouse Polyclonal(Large Chain). Recognizes Rubisco Mouse Polyclonal(Large Chain) from Various Plants. This antibody is Unconjugated. Tested in the following application: WB;WB:1:2000-5000

Rubisco Mouse Polyclonal Antibody(Large Chain)
CSB-PA060093-100ul 100ul
EUR 316
Description: A polyclonal antibody against Rubisco Mouse Polyclonal(Large Chain). Recognizes Rubisco Mouse Polyclonal(Large Chain) from Various Plants. This antibody is Unconjugated. Tested in the following application: WB;WB:1:2000-5000

Active Calpain 1, Large Subunit (CAPN1)
4-APB964Ra01
  • EUR 749.60
  • EUR 304.00
  • EUR 2536.00
  • EUR 912.00
  • EUR 1724.00
  • EUR 565.00
  • EUR 6190.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Calpain 1, Large Subunit expressed in: E.coli

Active Calpain 1, Large Subunit (CAPN1)
4-APB964Ra02
  • EUR 749.60
  • EUR 304.00
  • EUR 2536.00
  • EUR 912.00
  • EUR 1724.00
  • EUR 565.00
  • EUR 6190.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Calpain 1, Large Subunit expressed in: E.coli

Disposable Latex Gloves, Large, 100/Box
GL003L 1PK, 100UNIT
EUR 71

Stainless Steel Beads 11mm (Large Pack)
SSB110-100 100pack
EUR 282
Description: Stainless steel beads. 11mm. Pack of 100. Non-sterile.

B-Cell Leukemia/Lymphoma Extra Large
PR27256 50 ug
EUR 318

Human Large Intestine Microvascular Endothelial Cells
HEC16 500,000+ Cells Frozen
EUR 1080

STAT Universal Animal IHC KIT-large
329ANK-60 Large Kit
EUR 1088

Rubisco (Large Chain) Monoclonal Antibody (9Y6)
A01110-005ml 0.05ml
EUR 147
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein

Rubisco (Large Chain) Monoclonal Antibody (9Y6)
A01110-02ml 0.2ml
EUR 332
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein

Rubisco (Large Chain) Monoclonal Antibody (9Y6)
A01110-02ml5 0.2ml×5
EUR 920
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein

Rubisco (Large Chain) Monoclonal Antibody (9Y6)
A01110HRP-005ml 0.05ml
EUR 180
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogen and conjugated to HRP. The antibody is produced in mouse by using as an immunogen recombinant protein

Rubisco (Large Chain) Monoclonal Antibody (9Y6)
A01110HRP-02ml 0.2ml
EUR 398
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogen and conjugated to HRP. The antibody is produced in mouse by using as an immunogen recombinant protein

Rubisco (Large Chain) Monoclonal Antibody (9Y6)
A01110HRP-02ml5 0.2ml×5
EUR 1265
Description: A monoclonal antibody for detection of Rubisco Large Chain) from Plants. This Rubisco Large Chain) antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogen and conjugated to HRP. The antibody is produced in mouse by using as an immunogen recombinant protein

Discs Large Homolog 4 (DLG4) Antibody
20-abx125325
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul

Calpain 1, Large Subunit (CAPN1) Antibody
20-abx128598
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Discs, Large Homolog 3 (DLG3) Antibody
20-abx129226
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Large Multifunctional Peptidase 2 (LMP2) Antibody
20-abx129728
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Discs, Large Homolog 5 (DLG5) Antibody
20-abx131277
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Discs, Large Homolog 5 (DLG5) Antibody
20-abx131278
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Calpain 2, Large Subunit (CAPN2) Antibody
20-abx109593
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Calpain 2, Large Subunit (CAPN2) Antibody
20-abx111330
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Discs, Large Homolog 3 (DLG3) Antibody
20-abx112100
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Discs, Large Homolog 5 (DLG5) Antibody
20-abx112101
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Disks Large Homolog 1 (DLG1) Antibody
20-abx124281
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Large Multifunctional Peptidase 2 (LMP2) Antibody
20-abx319932
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Disks Large Homolog 1 (DLG1) Antibody
20-abx317333
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Disks Large Homolog 2 (DLG2) Antibody
20-abx338845
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Discs Large Homolog 4 (DLG4) Antibody
20-abx004732
  • EUR 495.00
  • EUR 356.00
  • 100 ul
  • 50 ul

Large Multifunctional Peptidase 7 (LMP7) Antibody
20-abx103454
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Large Multifunctional Peptidase 7 (LMP7) Antibody
20-abx103455
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

KRAS/GNAS-testing was considerably superior to CEA (P = 0,0209) and cytology (P = 0.0016). In conclusion, KRAS/GNAS-testing by deep focused NGS is an acceptable technique to tell apart mucinous from non-mucinous pancreatic lesions, suggesting its utilization as a single diagnostic check. Outcomes have to be confirmed in a bigger cohort. This text is protected by copyright. All rights reserved.